Turning stem cells into human eggs

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Stem cell derived germ cells growing in one of our cultures
Our Mission

We want to help parents have kids, and we aspire to make future generations healthier.

 

We are working on a technology that would give women the opportunity to have children well into their forties and fifties, eliminate barriers for couples suffering from infertility, and potentially allow male-male couples to have biological children.

 

Long term, this technology could be a critical platform allowing for widespread genetic screening of embryos. If proven safe, it could even enable for genetic editing to eliminate and reduce the risk of devastating diseases for future generations – such as Alzheimer’s, heart disease and many different types of cancers.

 

This could become one of the most important technologies ever created.

Our Technology

In our lab, we reconstitute the process under which egg cells would normally develop inside the female body. We generate induced pluripotent stem cells from blood samples. We then shepherd these stem cells through the various steps that they would normally undergo as they develop to become viable eggs.

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We and others have shown that this technology works to make viable mouse eggs, and it can be used to make healthy, live mice. We are working on translating this technology to humans with the aim to make it a safe and accessible reproductive treatment.

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Our current focus is to create a proof of concept human egg, and develop rigorous process optimization and quality control measures to ensure that the eggs are healthy.

We do not take the development of this technology lightly. Our hope is that it will one day be used to bring healthy kids into the world, so we must hold ourselves to very high safety and ethical standards. Our plan will be to work closely with scientific, regulatory and ethical experts to ensure this technology develops safely and responsibly.

Our Team
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Abbie Groff

Associate Director
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Alex Schubert

Chief of Staff
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Alyssa Miller

Associate Director
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Anouk Killaars

Assay Scientist
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Benner Alves

Senior Scientist
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Bianka Seres

Head of Engineering / COO
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Erika Paulson

Scientist
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Jason Lee

Senior Scientist
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Jen Trecartin

Research Associate
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Jim Koman

Lab Manager
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Kele Alves

Senior Scientist
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Mariah Dunlap

Senior Scientist
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Mariela Myers

Histology Lead
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Matt Krisiloff

CEO
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Mikelle Foster

Associate Scientist
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Pablo Hurtado

CSO
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Rhishikesh Bargaje

Associate Director
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Ronald Pandoy

Associate Scientist
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Savannah Bever

Associate Scientist
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Silvia Llonch

Scientist
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Teri Ord

Senior Associate Scientist
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Tiama Hamkins-Indik

Senior Scientist
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Tisha Bohr

Scientist
Careers

A research company setting like ours is optimally set up to tackle a difficult problem like this.

We believe we have created a highly effective and open research environment, where everyone is united by the same goal. We are working on a difficult problem, and we are neither encumbered by limited resources, nor a need for individual team members to focus in isolation on their own projects for their own publications.

We think this type of research company serves as a model environment for how research should be done, and we invite you to come see for yourself.

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Current Openings
Senior Technician
Berkeley, CA

Help us with processing tissue samples.

Bioengineer
Berkeley, CA

Help us build new culture methods to generate human eggs from stem cells.

Gene and Cell Editing Scientist
Berkeley, CA

Help us manipulate and edit cells to support egg cell development.

Stem Cell Scientist
Berkeley, CA

Help develop stem cell differentiation protocols.

Associate Scientist
Berkeley, CA

Help drive cell production and experiment analysis. qPCR and/or cell differentiation experience strongly desired.